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Simulated Microgravity Influences VEGF, MAPK, and PAM Signaling in Prostate Cancer Cells.
Hybel TE, Dietrichs D, Sahana J, Corydon TJ, Nassef MZ, Wehland M, Krüger M, Magnusson NE, Bauer J, Utpatel K, Infanger M, Grimm D, Kopp S. Hybel TE, et al. Int J Mol Sci. 2020 Feb 13;21(4):1263. doi: 10.3390/ijms21041263. Int J Mol Sci. 2020. PMID: 32070055 Free PMC article.
Prostate cancer is one of the leading causes of cancer mortality in men worldwide. An unusual but unique environment for studying tumor cell processes is provided by microgravity, either in space or simulated by ground-based devices like a random positioning machine (RPM). …
Prostate cancer is one of the leading causes of cancer mortality in men worldwide. An unusual but unique environment for studying tum …
Three-Dimensional Growth of Prostate Cancer Cells Exposed to Simulated Microgravity.
Dietrichs D, Grimm D, Sahana J, Melnik D, Corydon TJ, Wehland M, Krüger M, Vermeesen R, Baselet B, Baatout S, Hybel TE, Kahlert S, Schulz H, Infanger M, Kopp S. Dietrichs D, et al. Front Cell Dev Biol. 2022 Feb 17;10:841017. doi: 10.3389/fcell.2022.841017. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35252204 Free PMC article.
Prostate cancer metastasis has an enormous impact on the mortality of cancer patients. ...After 24 h of exposure, in the MCS group we measured an increase in ACTB, MSN, COL1A1, LAMA3, FN1, TIMP1, FLT1, EGFR1, IL1A, IL6, CXCL8, and HIF1A mRNA expression, and in the A …
Prostate cancer metastasis has an enormous impact on the mortality of cancer patients. ...After 24 h of exposure, in the MCS group we …
Aberrant promoter methylation of laminin-5-encoding genes in prostate cancers and its relationship to clinicopathological features.
Sathyanarayana UG, Padar A, Suzuki M, Maruyama R, Shigematsu H, Hsieh JT, Frenkel EP, Gazdar AF. Sathyanarayana UG, et al. Clin Cancer Res. 2003 Dec 15;9(17):6395-400. Clin Cancer Res. 2003. PMID: 14695140
The concordances between loss of expression and methylation for the three genes were 100, 100, and 83%, respectively. The frequency of methylation of LN5-encoding genes in prostate cancers and nonmalignant prostate tissues, respectively, were: 44 and 12% for LAMA …
The concordances between loss of expression and methylation for the three genes were 100, 100, and 83%, respectively. The frequency of methy …